Profile: Boston Biochem, Inc. produces ubiquitin proteasome pathway products. Ubiquitin proteasome pathway (UPP) is the principal mechanism for protein catabolism in the mammalian cytosol and nucleus. Our highly regulated UPP affects a wide variety of cellular processes and substrates & defects in the system can result in the pathogenesis of several important human diseases. We also offer a wide variety of contract and consulting services customized to meet biomedical research needs. Some of our deconjugating enzymes include isopeptidase, UCH-L3, UCH-L1, and His&sub6; Ataxin3.