Laser-Based Point Scanning Confocal Microscopes Manufacturers

In laser-based point scanning confocal microscope, the excitation laser source is scanned across the specimen in a point-by-point raster pattern, so that, over time, a complete image of the focal plane is collected. The emitted light is then collected by the objective, passed through a pinhole aperture and detected by a photomultiplier tube (PMT). The resulting image is reconstructed and displayed by a computer. It offers some extraordinary advantages. It allows extremely thin optical sectioning of specimens, permitting the viewing of structures and intracellular features. It offers the highest level of confocality and the ability to do very thin optical sections.